Abstract Library

#622 Evaluation of Mucin and Neuroendocrine Expression in Diffuse Gastric Cancer with Signet Ring Cell Morphology

Introduction: A proportion of diffuse gastric carcinoma, according to the Lauren classification system, has signet ring cell morphology. Signet ring cells are characterized by a peripherally placed nucleus and a central amorphous substance, which is reported to be mucin based on Periodic Acid Schiff positivity (PAS). PAS is not a specific staining method for mucin. Neuroendocrine expression has previously been reported in tumor cells in diffuse type gastric cancer.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Sørdal �

Authors: Sørdal �, Qvigstad G, Nordrum I, Waldum H,

Keywords: gastric signet ring cell carcinoma, mucin, neuroendocrine markers, PAS,

#558 MANECs Among Colorectal Signet Ring Cell Carcinomas

Introduction: The mixed adenoneuroendocrine carcinomas (MANEC, WHO 2010) are neoplasms with heterogeneous morphology, whose mixed nature may be difficult to recognize.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Hermann G, Yarom N, Konukiewitz B, Sandbank J, Klöppel G,

Keywords: manec, signet ring cell carcinoma, colon, rectum,